Acriflavine Hydrochloride

CAS No. 8063-24-9

Acriflavine Hydrochloride( Acriflavine HCl )

Catalog No. M27171 CAS No. 8063-24-9

Acriflavine Hydrochloride is a HIF-1α inhibitor. It acts by targeting HIF-1α-mediated pathways and decreasing the level of PGK1, VEGF, and HIF-1α in vitro and in vivo.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Acriflavine Hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Acriflavine Hydrochloride is a HIF-1α inhibitor. It acts by targeting HIF-1α-mediated pathways and decreasing the level of PGK1, VEGF, and HIF-1α in vitro and in vivo.
  • Description
    Acriflavine Hydrochloride is a HIF-1α inhibitor. It acts by targeting HIF-1α-mediated pathways and decreasing the level of PGK1, VEGF, and HIF-1α in vitro and in vivo.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Acriflavine HCl
  • Pathway
    Angiogenesis
  • Target
    HIF/HIF Prolyl-hydroxylase
  • Recptor
    Antifungal
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    8063-24-9
  • Formula Weight
    259.74
  • Molecular Formula
    C14H14ClN3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    [Cl-].C[n+]1c2cc(N)ccc2cc2ccc(N)cc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Gurram RK, et al. Caerulomycin A enhances transforming growth factor-β (TGF-β)-Smad3 protein signaling by suppressing interferon-γ (IFN-γ)-signal transducer and activator of transcription 1 (STAT1) protein signaling to expand regulatory T cells (Tregs). J Biol Chem. 2014 Jun 20;289(25):17515-28.
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